What are the potential issues when moving your drive from one Mac to another?
I think a lot of us have booted from other Mac's system disks before, but are there any potential long-term issues with swapping your main hard drive back and forth between machines? (Besides the obvious potential for physical damage, of course.)
I can imagine a whole range of issues that might crop up -- from things like stored encryption keys failing, to apps or services that look for unique machine IDs, like MAC addresses -- but if possible I'd really like to avoid drive duping, disk images, and incremental backups / transfers with a tool like Carbon Copy Cloner.
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As Zeke notes, iTunes reauthorization may be an issue. I would avoid updating Time Machine if you can -- the TM identifiers are tied to the source disk UUID, not the motherboard, but it might still get hinky. A CCC or SuperDuper! backup once or twice during the swapped week should keep you covered.
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Whenever I've done this in the past I've never run into any issues. I know you want to avoid it, but I highly recommend cloning it just once early on so that you'll have peace of mind in knowing you can always revert back to it if something really weird happens. Knowing that I have a week-old SuperDuper clone ready just-in-case definitely makes me feel better about doing this. Other than that, avoiding software installs and updates is probably a good idea as acasper said.
Thankfully, in my experience at least, Apple has always come through early with in-house repairs, so you probably won't have to deal with this for too long.
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