I can be browsing a page, go to click a link and it wont register the first click so I'll have to click it a second time. It would be comparable to a window losing focus and needing a click before the window gains focus. When using the Magic Mouse I do not have this issue at all, it's only when I switch the Anywhere MX. The mouse is compatibile with Mac OSX so I know it's not that.

Anyone have ideas or suggestions?

I'm a big fan of Logitech's Anywhere Mouse MX - it has a dual mode scroll wheel, it tracks on glass, and it's just the right size to be both portable and useful. But it uses a tiny RF receiver that eats up one of the two slots on my MacBook Air, and there are (many) times when I'm forced to choose between connecting a modem or a mouse. All this would be solved if Logitech made a Bluetooth version, but they don't. The V470 doesn't work on glass (a too-common material for desks in hotel rooms) and... Read more →

I am not sure if there is a way to control it or if I can control this behavior. I have setpoint software installed and I do not see any option there. If anyone else has figured out how to change this behavior, please let me know